Didier azoulay biography definition
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Glenn Ligon
Glenn Ligon (b. 1960) is spruce up artist years and critical in Newborn York. In every nook his pursuit, Ligon has pursued let down incisive enquiry of Inhabitant history, information, and intercourse across bodies of rip off that found critically shift the legacies of contemporary painting swallow conceptual add to. He attained his BA from Wesleyan Campus (1982) extremity attended interpretation Whitney Museum Independent Read Program (1985). In 2011, the Whitney Museum of Land Art held a mid-career retrospective, ‘Glenn Ligon: AMERICA,’ organized harsh Scott Rothkopf, that voyage nationally. Urgent solo exhibitions include ‘Post-Noir,’ Carre d’Art, Nîmes (2022); ‘Glenn Ligon: Call promote Response,’ Metropolis Arts Focal point, London, UK (2014); and ‘Glenn Ligon – Some Changes,’ The Selfgovernment Plant Center for Coeval Art, Toronto, Canada impressive then travel internationally (2005). Select curatorial projects include ‘Grief and Grievance,’ New Museum, New Royalty NY (2021); ‘Blue Black,’ Publisher Arts Scaffold, St. Prizefighter MO (2017); and ‘Glenn Ligon: Encounters and Collisions,’ Nottingham Coeval and Be of assistance Liverpool, UK (2015). Ligon’s work has been shown in major international exhibitions, including the Venezia Biennale (2015, 1997), Songwriter Biennial (2014), Istanbul Biennial (2019, 2011) build up Documenta XI (2002).
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Resilience after severe critical illness: a prospective, multicentre, observational study (RESIREA)
- Research
- Open access
- Published:
- Alice Mathieu1,
- Jean Reignier2,3,53,
- Amélie Le Gouge4,5,
- Gaetan Plantefeve6,
- Jean-Paul Mira7,
- Laurent Argaud8,
- Pierre Asfar9,
- Julio Badie10,
- Nicolae-Vlad Botoc11,
- Hoang-Nam Bui12,
- Delphine Chatellier13,
- Louis Chauvelot14,
- Christophe Cracco15,
- Michael Darmon16,
- Agathe Delbove17,
- Jérôme Devaquet18,
- Louis-Marie Dumont19,
- Olivier Gontier20,
- Samuel Groyer21,
- Yannick Hourmant22,
- Samir Jaber23,24,
- Fabien Lambiotte25,
- Benjamin Madeux26,
- Julien Maizel27,
- Olivier Martinet28,
- Virginie Maxime29,30,
- Emmanuelle Mercier31,
- Mai-Anh Nay32,
- Saad Nseir33,34,
- Gael Piton35,36,
- Jean-Pierre Quenot37,38,39,
- Anne Renault40,
- Jean-Philippe Rigaud41,
- Francis Schneider42,
- Michel Sirodot43,
- Bertrand Souweine44,
- Fabienne Tamion45,
- Didier Thévenin46,
- Nathalie Thieulot-Rolin47,
- Francois Tinturier48,
- Patrice Tirot49,
- Isabelle Vinatier50,
- Christophe Vinsonneau51,
- Jean-Baptiste Lascarrou2,3,
- Alexandra Laurent1,52,54,
- the NUTRIREA-3 Trial Investigators &
- the Clinical Research In Intensive Car
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Abstract
An increasing number of noncoding RNAs (ncRNAs) have been implicated in various human diseases including cancer; however, the ncRNA transcriptome of hepatocellular carcinoma (HCC) is largely unexplored. We used CAGE to map transcription start sites across various types of human and mouse HCCs with emphasis on ncRNAs distant from protein-coding genes. Here, we report that retroviral LTR promoters, expressed in healthy tissues such as testis and placenta but not liver, are widely activated in liver tumors. Despite HCC heterogeneity, a subset of LTR-derived ncRNAs were more than 10-fold up-regulated in the vast majority of samples. HCCs with a high LTR activity mostly had a viral etiology, were less differentiated, and showed higher risk of recurrence. ChIP-seq data show that MYC and MAX are associated with ncRNA deregulation. Globally, CAGE enabled us to build a mammalian promoter map for HCC, which uncovers a new layer of complexity in HCC genomics.
Hepatocellular carcinoma (HCC) accounts for 70%–85% of total liver cancers. The major risk factors of HCC are chronic HBV and HCV infections and alcohol (Jemal et al. 2011). The development of HCC is a heterogeneous multistep process associated with genetic alteration and dysregulation of gene expression. Recent whole-ge