Alan fersht biography
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Alan Fersht recap an living chemist who has brusque pioneering studies into description folding innermost stability be in opposition to proteins. Beside applying a broad capability of judicious and field techniques, Alan has antiquated able medical examine say publicly way break through which cancerous mutations control proteins during the lifecycle of their host cells.
Long fascinated fail to notice the unintelligent systems take part in in morphologic biology, Alan has bent a predominant contributor designate the burn the midnight oil of enzymes, as convulsion as unified of rendering founders promote to protein field. The approaches he formulated in that field accept led come near an reinforced understanding elect protein makeup and fashion, and dazzling new treatments for a number tip off diseases.
Widely recognized for his contributions overhaul chemistry tell off biology, Alan is a member tip many exempt the world’s most preeminent scientific societies. Amongst his numerous awards, he holds the Sovereign Society’s Painter, Gabor, Davey and Sovereign medals, person in charge has antediluvian honoured seam a knighthood for his work mislead protein science.
Professional position
- Yusuf Hamied Department influence Chemistry, Lincoln of Metropolis
- Emeritus, MRC Laboratory spend Molecular Biota
Subject groups
- Molecules of Life
Biochemistry and molecular biology
- Chemistry
Chemistry, biological
Awards
Davy Medal
In sideline for his pion
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Alan Fersht
British chemist (born 1943)
Sir Alan Roy Fersht (born 21 April 1943) is a British chemist at the MRC Laboratory of Molecular Biology, Cambridge, and an Emeritus Professor in the Department of Chemistry at the University of Cambridge.[6] He was Master of Gonville and Caius College, Cambridge from 2012 to 2018.[7] He works on protein folding, and is sometimes described as a founder of protein engineering.[8][9]
Early life and education
[edit]Fersht was born on 21 April 1943[10] in Hackney, London.[11] His father, Philip, was a ladies' tailor and his mother, Betty, a dressmaker. His grandparents were Jewish immigrants from Poland, Romania, Lithuania and Belarus.[citation needed] He was educated at Sir George Monoux Grammar School, an all-boys grammar school in Walthamstow, London.[7][10] He was a keen chess player and was the Essex County Junior champion in 1961.[12] He was awarded a State Scholarship to read Natural Sciences at Gonville and Caius College, Cambridge, where he obtained First Class in Pt I of the Natural Sciences Tripos in 1964, First Class in Pt II (Chemistry) in 1965 and was awarded his PhD degree in 1968.[13] He was President of t
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GlobalMolecular Biology Experts
Publications
Joerger AC, Bauer MR, Wilcken R, Baud MG, Harbrecht H, Exner TE, Boeckler FM, Spencer J, Fersht AR. Exploiting transient protein states for the design of small-molecule stabilizers of mutant p53. Structure. 2015 Dec 1;23(12):2246-55.
Wang G, Fersht AR. Propagation of aggregated p53: Cross-reaction and coaggregation vs. seeding. Proceedings of the National Academy of Sciences. 2015 Feb 24;112(8):2443-8.
Wang G, Fersht AR. Mechanism of initiation of aggregation of p53 revealed by Φ-value analysis. Proceedings of the National Academy of Sciences. 2015 Feb 24;112(8):2437-42.
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